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馬偕醫學院 Mackay Medical College
師資陣容  
吳子維
(Wu, Tzu-Wei)
職稱 副教授
主要學歷

南加州大學神經科學博士 
國立陽明大學微生物及免疫學研究所碩士 
國立清華大學生命科學系學士

主要經歷

Manager,中央研究院電生理暨鈣離子影像核心實驗室 兼任助理教授,國立台北科技大學生物科技研究所 博士後研究,中央研究院分子生物研究所 助教,南加州大學生物科學系

現職

馬偕醫學院醫學系副教授

教學專長

普通生物學、細胞生物學、神經科學、神經保護機制學、老化學、電生理學

學術期刊
  1. Tzu-Wei Wu*, Chun-Chieh Liu, Chung-Lieh Hung, Chih-Hsien Yen, Yih-Jer Wu, Li-Yu Wang, Hung-I Yeh.  Genetic profiling of young and aged endothelial progenitor cells in hypoxia. PLOS ONE. Vol.13-No.4:e0196-e0217. Apr. 2018. (SCI)
  2. Chao-LiangChou, Yih-Jer Wu, Chung-Lieh Hung, Chun-Chieh Liu, Shwun-De Wang, Tzu-Wei Wu, Li-Yu Wang, Hung-I. Yeh .  Segment-specific prevalence of carotid artery plaque and stenosis in middle-aged adults and elders in Taiwan: A community-based study.. Journal of the Formosan Medical Association. Vol.17:30708-30708. Jan. 2018. (SCI)
  3. Tzu-Wei Wu, Chung-Lieh Hung, Chun-Chieh Liu, Yih-Jer Wu, Li-Yu Wang, Hung-I Yeh.  Associations of Cardiovascular Risk Factors with Carotid Intima-Media Thickness in Middle-Age Adults and Elders.. Journal of Atherosclerosis and Thrombosis. Vol.24-No.7:677-686. Jul. 2017. (SCI)
  4. Yi-Cheng Chen, Kuang-Hung Hsu, Hung-Yi Chiou, Yue-Li Juang, Tzu-Wei Wu, Chung-Lieh Hung, Chun-Chieh Liu, Yih-Jer Wu, Hung-I Yeh, Li-Yu Wang.  Associations of lipid-related genetic markers with elevated carotid intima-media thickness in middle-age adults and elders.. International Journal of Cardiology. Vol.189:264-266. Jun. 2015. (SCI)
  5. Tzu-Wei Wu, Chuen-Fei Chen, Sheng-Kai Lai,  Hans Hsienhong Lin, Chen-Chung Chu, Li-Yu Wang.  SNP rs7770370 in HLA-DPB1 loci is the major genetic determinant of response to booster hepatitis B vaccination-results of a genome-wide association study.. Journal of Gastroenterology and Hepatology. Vol.30-No.5:891-899. May. 2015. (SCI)
  6. Tzu-Wei Wu,  Hsin-Lung Chan,  Chung-Lieh Hung,  I-Jung Lu,  Shwun-De Wang, Shih-Wei Wang, Yih-Jer Wu,  Li-Yu Wang, Hung-I Yeh, Yau-Huei Wei.  Differential patterns of effects of age and sex on metabolic syndrome in Taiwan: Implication for the inadequate internal consistency of the current criteria. Diabetes Research and Clinical Practice. Vol.105-No.2:239-244. Aug. 2014. (SCI)
  7. Tzu-Wei Wu, Chen-Chung Chu, Huei-Wen Chang Liao, Sheng-Kai Lin, Tzu-Ying Ho, Marie Lin, Hans Hsienhong Lin, Li-Yu Wang.  HLA-DPB1 and anti-HBs titers kinetics in hepatitis B booster recipients who completed primary hepatitis B vaccination during infancy.. Genes and Immunity. Vol.15:47-53. Nov. 2013. (SCI)
  8. Tzu-Wei Wu, Chen-Chung Chu, Tzu-Ying Ho,  Huei-Wen Chang Liao, Sheng-Kai Lin, Marie Lin, Hans Hsienhong Lin, Li-Yu Wang.  Responses to booster hepatitis B vaccination are significantly correlated with genotypes of human leukocyte antigen (HLA)-DPB1 in neonatally vaccinated adolescents.. Human Genetics. Vol.132:1131-1139. Oct. 2013. (SCI)
  9. Tzu-Wei Wu, Hans Hsienhong Lin, Li-Yu Wang.  Chronic hepatitis B infection in adolescents who had received primary infantile vaccination.. Hepatology. Vol.57-No.1:37-45. Jan. 2013. (SCI)
  10. T.-w. Wu, S Chen, RD. Brinton.  Membrane estrogen receptors mediate calcium signaling and MAP kinase activation in individual hippocampal neurons.. Brain Research. Vol.1379:34-43. Jan. 2011. (SCI)
  11. K.J. Tsai, C.H. Yang, Y.H. Fang, K.H. Cho, W.L. Chien, W.T. Wang, T.-w. Wu, C.P. Lin, W.M. Fu, C.K. Shen.  Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U.. Journal of Experimental Medicine. Vol.207:1661-1673. Jul. 2010. (SCI)
  12. T.-w Wu, W. Li, H. Li.  Netrin-1 attenuates ischemic stroke-induced apoptosis. Neuroscience. Vol.156:475-482. Jan. 2008. (SCI)
  13. W. N. Lian, T.-w. Wu, R. L. Dao, Y. J. Chen, C. H. Lin.  Deglycosylation of Na+/K+-ATPase causes the basolateral protein to undergo apical targeting in polarized hepatic cells. Journal of Cell Science. Vol.119:11-22. Jan. 2006. (SCI)
  14. T.-w. Wu, J. M. Wang, S. Chen, R. D. Brinton.  17Beta-Estradiol Induced Ca2+ Influx via L-type Calcium Channels Activates the SRC/ERK/cyclic-AMP Response Element Binding Protein Signal Pathway and BCL-2 Expression in Rat Hippocampal Neurons: A Potential Initiation Mechanism for Estrogen-Induced Neuroprotection.. Neuroscience. Vol.135:59-72. Sep. 2005. (SCI)
  15. L. Zhao, T.-w. Wu, R.D. Brinton.  Estrogen Receptor Subtypes Alpha and Beta Contribute to Neuroprotection and Increased Bcl-2 Expression in Primary Hippocampal Neurons.. Brain Research. Vol.1010:22-34. Jun. 2004. (SCI)
研討會
  1. Tzu-Wei Wu*, Li-Yu Wang, Hung-I Yeh.  BCL2/adenovirus E1B 19 kd-Interacting Protein 3 Protected Young Endothelial Progenitor Cells from Hypoxia-Induced Apoptosis.. Keystone Symposia Conference: E1: Epigenetic and Metabolic Regulation of Aging and Aging-Related Dis. May. 2016.
  2. Tzu-wei Wu*.  Neuroprotective effect against hypoxia through dependent receptor pathway. 2011 Society for Neuroscience 41st annual meeting. Nov. 2011.
  3. Li-jung Wang, Tzu-wei Wu*.  The mechanistic study of netrin-1 protective effects against ischemic stroke.. 20th European Stroke Conference. May. 2011.
計畫
計畫起訖年月計畫名稱擔任職務
2016-08 ~
2017-07
探討晚期內皮起源細胞中BNIP3對低氧與繼代老化之反應: 強調微RNA機轉與臨床意義主持人
2016-08 ~
2017-07
新穎微型核糖核酸對於內皮起源細胞功能與相關血管疾病之調控(1/3)共同主持人
2015-08 ~
2018-07
B型肝炎疫苗反應性之全基因體相關研究: 強調人類白血球抗原相關基因的影響共同主持人
2014-08 ~
2015-07
B型肝炎疫苗反應性之全基因體相關研究: 強調人類白血球抗原相關基因的影響共同主持人
2014-08 ~
2016-07
探討晚期內皮起源細胞中BNIP3對低氧與繼代老化之反應: 強調粒線體機轉與臨床意義主持人
2013-08 ~
2014-07
B型肝炎疫苗反應性之全基因體相關分析-強調人類白血球抗原相關基因的影響共同主持人
2013-08 ~
2016-07
探討內皮起源細胞之老化:強調機轉、預防以及心血管疾病的應用共同主持人
2013-08 ~
2014-07
老化對低氧環境引發人類內皮起源細胞中BNIP-3 表現之影響主持人
2013-01 ~
2013-12
連續長期缺氧環境對內皮前驅細胞的影響共同主持人
2010-08 ~
2013-07
私立大學校院發展研發特色專案計畫-探討老化相關疾病之決定因素及機轉:強調粒線體失能的影響共同主持人
2010-08 ~
2012-07
Netrin-1對缺血性中風保護作用之機轉探討主持人
2009-08 ~
2010-07
Investigation of the role of dependence receptors in apoptotic neuronal diseases.主持人
個人興趣

棒球、踏青、電影欣賞

聯絡方式

tzuweiwu@mmc.edu.tw

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