馬偕醫學院 Mackay Medical College
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馬偕醫學院 Mackay Medical College
師資陣容  
王士維
(Wang, Shin-Wei)
職稱 副教授兼總務長
主要學歷

台灣大學藥理學研究所博士
台灣大學藥理學研究所碩士
高雄醫學大學藥學系學士

主要經歷

台灣大學藥理學研究所博士後研究員
台灣藥理學會會員
台灣粒線體醫學暨研究學會會員
美國癌症研究協會(AACR associate member)會員
歐洲肝臟研究協會(EASL member) 會員

教學專長

藥理學、藥效藥理評估、癌症治療學

研究專長
  1. 以細胞週期調控分子為作用標的,誘發細胞凋亡之抗癌藥物研發。
  2. 腫瘤微環境中抑制侵襲、轉移與血管新生作用之藥物研發與藥理機轉探討。
學術期刊
  1. Yu SY#, Wang SW#, Hwang TL, Wei BL, Su CJ, Chang FR*, Cheng YB*.  Components from the Leaves and Twigs of Mangrove Lumnitzera racemosa with Anti-Angiogenic and Anti-Inflammatory Effects. Marine Drugs. Vol.16-No.404:1-8. Oct. 2018. (SCI)
  2. Wei CY#, Wang SW#, Ye JW, Hwang TL, Chen MJ, Sung PJ, Chang TH, Chen JJ*.  New Anti-Inflammatory Aporphine and Lignan Derivatives from the Root Wood of Hernandia nymphaeifolia. Molecules. Vol.23-No.2286:1-12. Sep. 2018. (SCI)
  3. Tzeng HE, Tang CH, Wu SH, Chen HT, Fong YC, Lu YC, Chen WC, Huang HD, Lin CY*, Wang SW*.  CCN6-mediated MMP-9 activation enhances metastatic potential of human chondrosarcoma. Cell Death&Disease. Vol.9-No.955:1-14. Sep. 2018. (SCI)
  4. Su CM#, Tang CH#, Chi MJ, Lin CY, Fong YC, Liu YC, Chen WC, Wang SW*.  Resistin facilitates VEGF-C-associated lymphangiogenesis by inhibiting miR-186 in human chondrosarcoma cells. Biochemical Pharmacology. Vol.154:234-242. Aug. 2018. (SCI)
  5. Wang GS#, Shen YS#, Chou WY, Tang CH, Yeh HI, Wang LY, Yen JY, Huang TY, Liu SC, Yang CY, Lin TY, Chen C*, Wang SW*.  Senescence Induces Dysfunctions in Endothelial Progenitor Cells and Osteoblasts by Interfering Translational Machinery and Bioenergetic Homeostasis. International Journal of Molecular Sciences. Vol.19-No.1997:1-18. Jul. 2018. (SCI)
  6. Wang SW, Chen YR, Chow JM, Chien MH, Yang SF, Wen YC, Lee WJ, Tseng TW.  Stimulation of Fas/FasL-mediated apoptosis by luteolin through enhancement of histone H3 acetylation and c-Jun activation in HL-60 leukemia cells. Molecular Carcinogenesis. Vol.57:866-877. Jul. 2018. (SCI)
  7. Cheng LY, Chen CL, Kuo YH, Chang TH, Lin IW, Wang SW*, Chung MI*, Chen JJ*.  Polyprenylated polycyclic acylphloroglucinol: Angiogenesis inhibitor from Garcinia multiflora. Bioorganic & Medicinal Chemistry Letters. Vol.28:1860-1863. Jun. 2018. (SCI)
  8. Chen WC, Chung CH, Lu YC, Wu MH, Chou YC, Yen JY, Lai YW, Wang GS, Liu SC, Cheng JK, Wu YJ, Yeh HI, Wang LY, Wang SW*.  BMP-2 induces angiogenesis by provoking integrin α6 expression in human endothelial progenitor cells. Biochemical Pharmacology. Vol.150:256-266. Apr. 2018. (SCI)
  9. Chung CH, Hsu CC, Lee AS, Wang SW, Lin KT, Chang WL, Peng HC, Huang WC, Chung CH*.  4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppression. BMC Complementary and Alternative Medicine. Vol.18-No.108:1-11. Mar. 2018. (SCI)
  10. Lien MY, Tsai HC, Chang AC, Tsai MH, Hua CH, Wang SW, Tang CH*.  Chemokine CCL4 Induces Vascular Endothelial Growth Factor C Expression and Lymphangiogenesis by miR-195-3p in Oral Squamous Cell Carcinoma. Frontiers in Immunology. Vol.9-No.412:1-12. Mar. 2018. (SCI)
  11. Chen SR#, Wang SW#, Su CJ, Hu HC, Yang YL, Hsieh CT, Peng CC, Chang FR*, Cheng YB*.  Anti-Lymphangiogenesis Components from Zoanthid Palythoa tuberculosa. Marine Drugs. Vol.16-No.47:1-10. Jan. 2018. (SCI)
  12. Lee HP, Liu YC, Chen PC, Tai HC, Li TM, Fong YC, Chang CS, Wu MH, Chiu LP, Wang CJ, Chen YH, Wu YJ, Tang CH*, Wang SW*.  Tanshinone IIA inhibits angiogenesis in human endothelial progenitor cells in vitro and in vivo. Oncotarget. Vol.8:10921-10922. Dec. 2017. (SCI)
  13. Su SM, Wang IC, Liu SC, Sun Y, Jin L, Wang SW, Lee HP, Tseng WP, Tang CH*.  Hypoxia induced mitogenic factor (HIMF) triggers angiogenesis by increasing interleukin-18 production in myoblasts. Scientific Reports. Vol.7-No.7393:1-11. Aug. 2017. (SCI)
  14. Lin CY#, Wang SW#, Chen YL, Chow WY, Lin TY, Chen WC, Yang CY, Liu SC, Hsieh CC, Fong YC, Wang PC*, Tang CH*.  Brain-derived neurotrophic factor promotes VEGF-C-dependent lymphangiogenesis by suppressing miR-624-3p in human chondrosarcoma cells. Cell Death&Disease. Vol.8-No.2964:1-11. Aug. 2017. (SCI)
  15. Li CY, Lo IW, Wang SW, Hwang TL, Chung YM, Cheng YB, Tseng SP, Liu YH, Hsu YM, Chen SR, Hsu HC, Chang FR*, Wu YC*.  Novel 11-norbetaenone isolated from an entomopathogenic fungus Lecanicillium antillanum. Bioorganic & Medicinal Chemistry Letters. Vol.27:1978-1982. May. 2017. (SCI)
  16. Tsai CH, Tseng HE, Huang CY, Huang YL, Tsai CH, Wang SW, Wang PC, Chang AC, Fong YC, Tang CH*.  WISP-1 positively regulates angiogenesis by controlling VEGF-A expression in human osteosarcoma. Cell Death&Disease. Vol.8-No.2750:1-11. Apr. 2017. (SCI)
  17. Wang LH, Tsai HC, Cheng YC, Lin CY, Huang YL, Tsai CH, Xu GH, Wang SW, Fong YC, Tang CH*.  CTGF promotes osteosarcoma angiogenesis by regulating miR-543/angiopoietin 2 signaling. Cancer Letters. Vol.391:28-37. Apr. 2017. (SCI)
  18. Li TM, Liu SC, Huang YH, Huang CC, Hsu CJ, Tsai CH, Wang SW, Tang CH*.  YKL-40-Induced Inhibition of miR-590-3p Promotes Interleukin-18 Expression and Angiogenesis of Endothelial Progenitor Cells. International Journal of Molecular Sciences. Vol.18-No.920:1-14. Apr. 2017. (SCI)
  19. Chien MH, Lee TH, Lee WJ, Yeh YH, Li TK, Wang PC, Chen JJ, Chow JM, Lin YW, Hsiao M, Wang SW*, Hua KT*.  Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts. Cancer Letters. Vol.388:249-261. Mar. 2017. (SCI)
  20. Chen CY, Su CM, Hsu CJ, Huang CC, Wang SW, Liu SC, Chen WC, Fuh LJ*, Tang CH*.  CCN1 Promotes VEGF Production in Osteoblasts and Induces Endothelial Progenitor Cells Angiogenesis by Inhibiting miR-126 Expression in Rheumatoid Arthritis. Journal of Bone and Mineral Research. Vol.32:34-45. Jan. 2017. (SCI)
  21. Wang CQ, Huang YW, Wang SW, Huang YL, Tsai CH, Zhao YM, Huang BF, Xu GH, Fong YC, Tang CH*.  Amphiregulin enhances VEGF-A production in human chondrosarcoma cells and promotes angiogenesis by inhibiting miR-206 via FAK/c-Src/PKCδ pathway. Cancer Letters. Vol.385:261-270. Jan. 2017. (SCI)
  22. Lee MS, Wang SW, Wang GJ, Pang KL, Lee CK, Kuo YH, Cha HJ, Lin RK*, Lee TH*.  Angiogenesis inhibitors and anti-inflammatory agents from Phoma sp. NTOU4195. Journal of Natural Products. Vol.79:2983-2990. Dec. 2016. (SCI)
  23. Sun HL, Cui R, Zhou J, Teng KY, Hsiao YH, Nakanishi K, Fassan M, Luo Z, Shi G, Tili E, Kutay H , Lovat F, Vicentini C, Huang HL, Wang SW, Hung MC, Ghoshal K, Teng CM, Peng Y*, Croce CM*.  ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5. Cancer Cell. Vol.30:723-736. Nov. 2016. (SCI)
  24. Huang CY, Chang A, Chen HT, Wang SW, Lo YS, Tang CH*.  Adiponectin promotes VEGF-C-dependent lymphangiogenesis by inhibiting miR-27b through a CaMKII/AMPK/p38 signaling pathway in human chondrosarcoma cells. Clinical Science. Vol.130:1523-1533. Sep. 2016. (SCI)
  25. Tzeng HE, Chang AC, Tsai CH, Wang SW, Tang CH*.  Basic fibroblast growth factor promotes VEGF-C-dependent lymphangiogenesis via inhibition of miR-381 in human chondrosarcoma cells. Oncotarget. Vol.7:38566-38578. Jun. 2016. (SCI)
  26. Yang WH, Chang AC, Wang SW, Wang SJ, Chang YS, Chang TM, Hsu SK, Fong YC, Tang CH*.  Leptin promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-27b in human chondrosarcoma cells. Scientific Reports. Vol.6-No.28647:1-10. Jun. 2016. (SCI)
  27. Chien SY, Huang CY, Tsai CH, Wang SW, Lin YM, Tang CH*.  Interleukin-1β induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes. Clinical Science. Vol.130:667-681. May. 2016. (SCI)
  28. Yeh YH, Wang SW, Yeh YC, Hsiao HF, Li TK*.  Rhapontigenin inhibits TGF-β-mediated epithelial-mesenchymal-transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation. Oncology Reports. Vol.35:2887-2895. May. 2016. (SCI)
  29. Wang LH, Lin CY, Liu SC, Liu GT, Chen YL, Chen JJ, Chan CH, Lin TY, Chen CK,  Xu GH, Chen SS, Tang CH*, Wang SW*.  CCL5 promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-507 in human chondrosarcoma cells. Oncotarget. Vol.7:36896-36908. May. 2016. (SCI)
  30. Tai HC*, Tai TY, Yang WS, Wang SW, Yu HJ.  Associations between lower urinary tract dysfunction and glycemic control in women with type 2 diabetes: a cross-sectional study. Journal of Diabetes and Its Complications. Vol.30:415-419. Apr. 2016. (SCI)
  31. Lin CC, Chen PC, Lein MY, Tsao CW, Huang CC, Wang SW, Tang CH*, Tung KC*.  WISP-1 promotes VEGF-C–dependent lymphangiogenesis by inhibiting miR-300 in human oral squamous cell carcinoma cells. Oncotarget. Vol.7:9993-10005. Mar. 2016. (SCI)
  32. Lai YW, Wang SW, Chang CH, Liu SC, Chen YJ, Chi CW, Chiu LP, Chen SS, Chiu AW, Chung CH*.  Butein inhibits metastatic behavior in mouse melanoma cells through VEGF expression and translation-dependent signaling pathway regulation. BMC Complementary and Alternative Medicine. Vol.15-No.445:1-10. Dec. 2015. (SCI)
  33. Liao YY, Tsai HC, Chou PY, Wang SW, Chen CT, Lin YM, Chiang IP, Chang TM, Hsu SK, Chou MC, Tang CH, Fong YC.  CCL3 promotes angiogenesis by dysregulation of miR-374b/VEGF-A axis in human osteosarcoma cells. Oncotarget. Vol.7:1-16. Dec. 2015. (SCI)
  34. Lee HP, Lin CY, Shih JS, Fong YC, Wang SW, Li TM, Tang CH.  Adiponectin promotes VEGF-A-dependent angiogenesis in human chondrosarcoma through PI3K, Akt, mTOR, and HIF-α pathway. Oncotarget. Vol.6:36746-36761. Nov. 2015. (SCI)
  35. Su CM, Hsu CJ, Tsai CH, Huang CY, Wang SW, Tang CH.  Resistin Promotes Angiogenesis in Endothelial Progenitor Cells Through Inhibition of MicroRNA206: Potential Implications for Rheumatoid Arthritis. Stem Cells. Vol.33:2243-2255. Jul. 2015. (SCI)
  36. Chen YL, Tsaur ML, Wang SW, Wang TY, Hung YC, Lin CS, Chang YF, Wang YC, Shiue SJ, Cheng JK.  Chronic intrathecal infusion of mibefradil, ethosuximide and nickel attenuates nerve ligation-induced pain in rats. British of Anaesthesia. Vol.115:105-111. Jul. 2015. (SCI)
  37. Tzeng HE, Chen PC, Lin KW, Lin CY, Tsai CH, Han SM, Teng CL, Hwang WL, Wang SW, Tang CH.  Basic fibroblast growth factor induces VEGF expression in chondrosarcoma cells and subsequently promotes endothelial progenitor cell-primed angiogenesis. Clinical Science. Vol.129:147-158. Jul. 2015. (SCI)
  38. Chuang JY, Chen PC, Tsao CW, Chang AC, Lein MY, Lin CC, Wang SW, Lin CW, Tang CH.  WISP-1 a novel angiogenic regulator of the CCN family promotes oral squamous cell carcinoma angiogenesis through VEGF-A expression. Oncotarget. Vol.6:4239-4252. Feb. 2015. (SCI)
  39. Lin YH, Feng CH, Wang SW, Ko PY, Lee MH, Chen YL.  Determination of Nicotine in Tobacco by Chemometric Optimization and Cation-Selective Exhaustive Injection in Combination with Sweeping-Micellar Electrokinetic Chromatography. Journal of Analytical Methods in Chemistry. Vol.869719:1-8. Feb. 2015. (SCI)
  40. Hsiao WY, Jiang SJ, Feng CH, Wang SW, Chen YL.  Determining ultraviolet absorbents in sunscreen products by combining direct injection with micelle collapse on-line preconcentration capillary electrophoresis. Journal of Chromatography A. Vol.1383:175-181. Feb. 2015. (SCI)
  41. Lin GT, Huang YL, Tzeng HE, Tsai CH, Wang SW, Tang CH.  CCL5 promotes vascular endothelial growth factor expression and induces angiogenesis by down-regulating miR-199a in human chondrosarcoma cells. Cancer Letters. Vol.357:476-487. Feb. 2015. (SCI)
  42. Wang SW, Liu SC, Sun HL, Huang TY, Chan CH, Yang CY, Yeh HI, Huang YL, Chou WY, Lin YM, Tang CH.  CCL5/CCR5 axis induces vascular endothelial growth factor-mediated tumor angiogenesis in human osteosarcoma microenvironment. Carcinogenesis. Vol.36:104-114. Jan. 2015. (SCI)
  43. Yang WH, Chen JC, Hsu KH, Lin CY, Wang SW, Wang SJ, Chang YS, Tang CH.  Leptin increases VEGF expression and enhances angiogenesis in human chondrosarcoma cells. Biochimica et Biophysica Acta - General Subjects. Vol.1840:3483-3493. Dec. 2014. (SCI)
  44. Liu SC, Chuang SW, Hsu CJ, Tsai CH, Wang SW, Tang CH.  CTGF increases vascular endothelial growth factor-dependent angiogenesis in human synovial fibroblasts by increasing miR-210 expression. Cell Death and Disease. Vol.5-No.1485:1-12. Oct. 2014. (SCI)
  45. Lin CY, Hung SY, Chen HT, Tsou HK, Fong YC, Wang SW, Tang CH.  Brain-derived neurotrophic factor increases vascular endothelial growth factor expression and enhances angiogenesis in human chondrosarcoma cells. Biochemical Pharmacology. Vol.91:522-533. Oct. 2014. (SCI)
  46. Tai HC, Chang AC, Yu HC, Huang CY, Tsai YC, Lai YW, Sun HL, Tang CH, Wang SW*.  Osteoblast- derived WISP-1 increases VCAM-1 expression and enhances prostate cancer metastasis by down- regulating miR-126. Oncotarget. Vol.5:7589-7598. Sep. 2014. (SCI)
  47. Liu SC, Chen C, Chung CH, Wang PC, Wu NL, Cheng JK, Lai YW, Sun HL, Peng CY, Tang CH, Wang SW*.  Inhibitory effects of butein on cancer metastasis and bioenergetics modulation. Journal of Agricultural and Food Chemistry. Vol.62:9109-9117. Sep. 2014. (SCI)
  48. Chen YL, Jiang SJ, Feng CH, Wang SW, Lin YH, Liu PY.  Application of central composite design for the determination of exfoliating agents in cosmetics by capillary electrophoresis with electroosmotic flow modulation. Analytical Letters. Vol.47:1670-1682. Jun. 2014. (SCI)
  49. Chen JJ, Wang SW, Hsiao HY, Lee MS, Ju YM, Kuo YH, Lee TH.  Aliphatic Phenolic Ethers from Trichobotrys effuse. Journal of Natural Products. Vol.77:1097-1101. May. 2014. (SCI)
  50. Hsiao CJ, Hsiao G, Chen WL, Wang SW, Chiang CP, Liu LY, Guh JH, Lee TH, Chung CL.  Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. Journal of Natural Products. Vol.77:758-765. Apr. 2014. (SCI)
  51. Chen PC, Cheng HC, Wang J, Wang SW, Tai HC, Lin CW, Tang CH.  Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment. Oncotarget. Vol.5:1595-1608. Mar. 2014. (SCI)
  52. Wu MH, Huang CY, Lin JA, Wang SW, Peng CY, Cheng HC, Tang CH.  Endothelin-1 promotes vascular endothelial growth factor-dependent angiogenesis in human chondrosarcoma cells. Oncogene. Vol.33:1725-1735. Mar. 2014. (SCI)
  53. Yu HS, Wang SW, Chang AC, Tai HC, Yeh HI, Lin YM, Tang CH.  Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochemical Pharmacology. Vol.87:243-253. Jan. 2014. (SCI)
  54. Lo HM, Wang SW, Chen CL, Wu PH, Wu WB.  Effects of all-trans retinoic acid, retinol, and β-carotene on murine macrophage activity. Food & Function. Vol.5:140-148. Jan. 2014. (SCI)
  55. Chen-Ming Su, Shih-Wei Wang, Tzong-Huei Lee, Wen-Pei Tzeng, Che-Jen Hsiao, Shih-Chia Liu, Chih-Hsin Tang.  Trichodermin induces cell apoptosis through mitochondrial dysfunction and endoplasmic reticulum stress in human chondrosarcoma cells. Toxicology and Applied Pharmacology. Vol.272:335-344. Oct. 2013. (SCI)
  56. Ching-Hu Chung, Chien-Hsin Chang, Shiou-Sheng Chen, Hsueh-Hsiao Wang, Juei-Yu Yen, Che-Jen Hsiao, Nan-Lin Wu, Yen-Ling Chen, Tur-Fu Huang, Po-Chuan Wang, Hung-I Yeh, Shih-Wei Wang*.  Butein inhibits angiogenesis of human endothelial progenitor cells via the translation dependent signaling pathway. Evidence-Based Complementary and Alternative Medicine. Vol.943187:1-10. Jun. 2013. (SCI)
  57. Huey-En Tzeng, Chun-Hao Tsai, Zi-Ling Chang, Chen-Ming Su, Shih-Wei Wang, Wen-Li Hwang, Chih-Hsin Tang.  Interleukin-6 induces vascular endothelial growth factor expression and promotes angiogenesis through apoptosis signal-regulating kinase 1 in human osteosarcoma. Biochemical Pharmacology. Vol.85:531-540. Feb. 2013. (SCI)
  58. Yen-Nien Chen, Tur-Fu Huang, Chien-Hsin Chang, Chun-Chieh Hsu, Kung-Tin Lin, Shih-Wei Wang, Hui-Chin Peng, Ching-Hu Chung.  Antirestenosis Effect of Butein in the Neointima Formation Progression. Journal of Agricultural and Food Chemistry. Vol.60:6832-6838. Jun. 2012. (SCI)
  59. Shih-Wei Wang, Hsing-Hsien Wu, Shih-Chia Liu, Po-Chuan Wang, Wen-Chieh Ou, Wen-Yi Chou, Yung-Shuen Shen, Chih-Hsin Tang.  CCL5 and CCR5 interaction promotes cell motility in human osteosarcoma. PLoS One. Vol.7-No.35101:1-11. Apr. 2012. (SCI)
  60. Tsai-Hua Chung, Jong-Kai Hsiao, Szu-Chun Hsu, Ming Yao, Yao-Chang Chen, Shih-Wei Wang, Mark Yen-Ping Kuo, Chung-Shi Yang, Dong-Ming Huang.  Iron oxide nanoparticle-induced epidermal growth factor receptor expression in human stem cells for tumor therapy. ACS Nano. Vol.12:9807-9816. Dec. 2011. (SCI)
  61. An-Chi Tsai, Shiow-Lin Pan, Cho-Hwa Liao, Jih-Hwa Guh, Shih-Wei Wang, Hui-Lung Sun, Yi-Nan Liu, Chien-Chih Chen, Chien-Chang Shen, Ya-Ling Chang, Che-Ming Teng.  Moscatilin, a bibenzyl derivative from the India orchid Dendrobrium loddigesii, suppresses tumor angiogenesis and growth in vitro and in vivo. Cancer Letters. Vol.292:163-170. Jun. 2010. (SCI)
  62. An-Chi Tsai, Shiow-Lin Pan, Hui-Lung Sun, Chih-Ya Wang, Chieh-Yu Peng, Shih-Wei Wang, Ya-Ling Chang, Sheng-Chu Kuo, Kuo-Hsiung Lee, Che-Ming Teng.  CHM-1, a new vascular targeting agent, induces apoptosis of human umbilical vein endothelial cells via p53-mediated death receptor 5 up-regulation. The Journal of Biological Chemistry. Vol.285:5497-5506. Feb. 2010. (SCI)
  63. Dong-Ming Huang, Jong-Kai Hsiao, Ying-Chun Chen, Li-Ying Chien, Ming Yao, Yin-Kai Chen, Bor-Sheng Ko, Szu-Chun Hsu, Lin-Ai Tai, Hui-Ying Cheng, Shih-Wei Wang, Chung-Shi Yang, Yao-Chang Chen.  The promotion of human mesenchymal stem cell proliferation by superparamagnetic iron oxide nanoparticles. Biomaterials. Vol.30:917-925. Aug. 2009. (SCI)
  64. Shih-Wei Wang, Shiow-Lin Pan, Yu-Chun Huang, Jih-Hwa Guh, Po-Cheng Chiang, Der-Yi Huang, Sheng-Chu Kuo, Kuo-Hsiung Lee, Che-Ming Teng.  CHM-1, a novel synthetic quinolone with potent and selective antimitotic antitumor activity against human hepatocellular carcinoma in vitro and in vivo. Molecular Cancer Therapeutics. Vol.7:350-360. Feb. 2008. (SCI)
  65. Shih-Wei Wang, Shiow-Lin Pan, Chieh-Yu Peng, Der-Yi Huang, An-Chi Tsai, Ya-Ling Chang, Jih-Hwa Guh, Sheng-Chu Kuo, Kuo-Hsiung Lee, Che-Ming Teng.  CHM-1 inhibits hepatocyte growth factor-induced invasion of SK-Hep-1 human hepatocellular carcinoma cells by suppressing matrix metalloproteinase-9 expression. Cancer Letters. Vol.257:87-96. Nov. 2007. (SCI)
  66. Ting-Chun Yeh, Po-Cheng Chiang, Tsai-Kun Li, Jui-Ling Hsu, Chun-Jung Lin, Shih-Wei Wang, Chieh-Yu Peng, Jih-Hwa Guh.  Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult. Biochemical Pharmacology. Vol.73:782-792. Mar. 2007. (SCI)
  67. Shiow-Lin Pan, Jih-Hwa Guh, Chieh-Yu Peng, Shih-Wei Wang, Ya-Ling Chang, Fong-Chi Cheng, Jau-Hsiang Chang, Sheng-Chu Kuo, Fang-Yu Lee, Che-Ming Teng.  YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models. Journal of Pharmacology and Experimental Therapeutics. Vol.314:35-42. Jul. 2005. (SCI)
  68. Shih-Wei Wang, Shiow-Lin Pan, Jih-Hwa Guh, Hui-Ling Chen, Dong-Ming Huang, Ya-Ling Chang, Sheng-Chu Kuo, Fang-Yu Lee, Che-Ming Teng.  YC-1 [3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl Indazole] exhibits a novel antiproliferative effect and arrests the cell cycle in G0-G1 in human hepatocellular carcinoma cells. Journal of Pharmacology and Experimental Therapeutics. Vol.312:917-925. Mar. 2005. (SCI)
研討會
  1. Shih-Wei Wang.  CCL5 promotes vascular endothelial growth factor-dependent angiogenesis in human osteosarcoma. The 13th Annual Meeting of Japanese Society of Medical Oncology. Jul. 2015.
  2. Shih-Wei Wang*.  Butein inhibits angiogenesis of human endothelial progenitor cells via the translation dependent signaling pathway. The 87th Annual Meeting of The Japanese Pharmacological Society. Mar. 2014.
  3. Shih-Wei Wang.  CCL5/CCR5 axis promotes VEGF production in human osteosarcoma cells. Ninth AACR-JCA Joint Conference: Breakthroughs in Basic and Translational Cancer Research. Feb. 2013.
  4. Shih-Wei Wang*.  CCL5 and CCR5 interaction promotes cell motility in human osteosarcoma. The 10th Annual Meeting of Japanese Society of Medical Oncology. Jul. 2012.
  5. Shih-Wei Wang*.  Moscatilin inhibits invasion by suppressing urokinase plasminogen activator expression through Akt inactivation in human hepatocellular carcinoma cells. American Association for Cancer Research 102nd Annual Meeting. Apr. 2011.
計畫
計畫起訖年月計畫名稱擔任職務
2018-08 ~
2019-07
新穎微型核糖核酸對於內皮起源細胞功能與相關血管疾病之調控(3/3)共同主持人
2017-08 ~
2018-07
新穎微型核糖核酸對於內皮起源細胞功能與相關血管疾病之調控(2/3)共同主持人
2017-08 ~
2020-07
由天然物探索新穎之血管新生抑制劑主持人
2016-08 ~
2017-07
新穎微型核糖核酸對於內皮起源細胞功能與相關血管疾病之調控(1/3)共同主持人
2016-08 ~
2017-07
探討CCL5調控骨肉瘤抗藥性之轉譯醫學研究主持人
2015-08 ~
2016-07
探討miRNA在CCL5調控骨肉瘤抗藥性之角色及機轉主持人
2013-08 ~
2016-07
探討內皮起源細胞之老化:強調機轉、預防以及心血管疾病的應用共同主持人
2012-08 ~
2015-07
探討CCL5調控骨肉瘤微環境之角色及機轉主持人
2011-08 ~
2012-07
探討CCL5調控骨肉瘤細胞轉移之角色及機轉主持人
2010-08 ~
2013-07
探討老化相關疾病之決定因素及機轉:強調粒線體失能的影響共同主持人
專利
期間專利名稱證書號發明人
2018-04-01 ~
2037-03-14
抑制血管新生之化合物及其製備方法I619706湯智昕;李宗徽;王士維;
2015-12-28 ~
2034-12-28
AURANTIAMIDE DIPEPTIDE DERIVATIVES FOR TREATMENT OR PREVENTION OF ANGIOGENESIS-RELATED DISEASESUS 9,872,882 B2Hung-I Yeh;Shih-Wei Wang;Ching-Hu Chung;Pei-Wen Hsieh;
編審
期間期刊名稱性質
2017-03-24 ~
2017-04-07
Oncotarget審查委員
2017-02-26 ~
2017-04-22
International Journal of Medical Sciences審查委員
2017-01-02 ~
2017-04-23
Biomedicine & Pharmacotherapy審查委員
2016-12-01 ~
2017-02-10
Oncoatrget審查委員
2016-11-29 ~
2016-12-03
Adaptive medicine審查委員
2016-11-03 ~
2016-11-28
Scientific Reports審查委員
2016-10-04 ~
2016-11-02
Molecular Therapy-Nucleic Acids審查委員
2016-08-31 ~
2016-09-14
Oncotarget審查委員
2016-08-21 ~
2016-08-29
Oncotarget審查委員
2016-06-20 ~
2016-07-02
Journal of Agricultural and Food Chemistry審查委員
2016-06-17 ~
2016-06-30
Oncotarget審查委員
2016-06-16 ~
2016-07-14
Oncotarget審查委員
2016-04-20 ~
2016-06-24
PLoS One審查委員
2016-01-22 ~
2016-01-24
International Journal of Medical Sciences審查委員
2016-01-05 ~
2016-01-14
Oncotarget審查委員
2015-11-06 ~
2015-11-24
Adaptive Medicine審查委員
2015-08-26 ~
2015-09-02
Journal of Agricultural and Food Chemistry審查委員
2015-08-12 ~
2015-09-22
PLoS One審查委員
2015-04-22 ~
2015-10-28
Journal of Translational Medicine審查委員
2015-01-21 ~
2015-02-14
Journal of Agricultural and Food Chemistry審查委員
2015-01-13 ~
2015-03-16
BioMed Research International審查委員
2014-09-11 ~
2014-11-10
Journal of Agricultural and Food Chemistry審查委員
2014-07-24 ~
2014-08-21
BioMed Research International審查委員
2014-05-31 ~
2014-06-21
BioMed Research International審查委員
2014-01-01 ~
2014-12-31
PLoS One審查委員
2013-11-19 ~
2013-12-18
BioMed Research International審查委員
2012-01-01 ~
2012-12-31
International Journal of Gerontology審查委員
2009-10-01 ~
2009-12-31
British Journal of Pharmacology審查委員
榮譽
期間榮譽名稱舉辦國家
2018-08-01 ~
2019-07-31
Special Outstanding Talent Award, Ministry of Science and Technology, 2018-2019.Taiwan
2017-10-13 ~
2017-10-14
2017 中華天然藥物學會 優秀天然藥物學術論文獎Taiwan
2017-08-01 ~
2018-07-31
Special Outstanding Talent Award, Ministry of Science and Technology, 2017-2018.Taiwan
2016-07-01 ~
2017-02-28
科技部105年度 指導大專生研究計畫 榮獲研究創作獎Taiwan
2014-08-01 ~
2016-07-31
Flexible Wage Award, Ministry of Education, 2014-2017.Taiwan
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